This study aims to determine the factors that affect the profitability of the banking company listed on the Jakarta Stock Exchange. The population in this study are all commercial banks that are listed in the Indonesia Stock Exchange period 2014 as many as 40 banks. The samples in this study using purposive sampling method, as many as 40 companies. The analysis technique used in this research is multiple regression. The results showed that together variable CAR and FDR significant effect on profitability, but only partially FDR variables that significantly influence profitability.