Antibacterial Effectiveness Test of Mulberry Leaf Extract (Mours Alba .L)Against Propionibacterium Acnes Using Agar Diffusion Method
DOI:
https://doi.org/10.19109/6ty7ry86Keywords:
Antibacterial, Mulberry leaf extract, Proponibacterium acne, Agar diffusionAbstract
Propionibacterium acnes bacteria are gram-positive bacteria that cause acne. This study aims to determine the antibacterial activity of mulberry leaf extract (Mours Alba L) against Propionibacterium acnes bacteria using the agar diffusion test method. Based on the results of phytochemical screening of mulberry leaf powder containing flavonoids, saponins, tannins, steroids, and triterpenoids which function as antibacterials. Based on the antibacterial activity test, mulberry leaf extract at concentrations of 20%, 30%, 40%, and 50% is effective in inhibiting the growth of Propionibacterium acnes bacteria. This can be proven from the results of the inhibition zone diameter, there is an increase in antibacterial effectiveness. Along with the increase in the concentration of mulberry leaf extract in inhibiting the growth of Propionibacterium acnes bacteria , namely at a concentration of 20%, the average diameter of the inhibition zone was 11.94 mm, then at a concentration of 30% the average diameter of the inhibition zone was 13.3 mm at a concentration of 40% the average diameter of the inhibition zone was 12.5 mm and at a maximum concentration of 50% the average diameter of the inhibition zone was 11.84 mm. The results of the study concluded that the most effective mulberry leaf extract inhibited the growth of Propionibacterium acnes bacteria at a concentration of 30% with a strong category.
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