Nanoencapsulation of Pelawan Stem Extract (Tristaniopsis merguensis Grifft.) Using Polycaprolactone (PCL)

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Published: Apr 6, 2025
DOI: https://doi.org/10.19109/wr4fqj14

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Robby Gus Mahardika
Department of Chemistry, Universitas Bangka Belitung
Shania Shakila
Departement of Chemistry, Universitas Bangka Belitung Indonesia
Widodo Budi Kurniawan
Departement of Physics, Universitas Bangka Belitung Indonesia
Ririn Amelia
Departement of Mathematics, Universitas Bangka Belitung Indonesia

Abstract

Formulation of nanoencapsulation using variations in the mass of Pelawan stem extract at (A) 0.15; (B) 0.25; and (C) 0.35 g combined with the addition of 0.5% PCL (Polycaprolactone) and Tween 80. Based on the analysis, the resulting nanocapsule sizes were 559.2, 447.2, and 297.0 nm, respectively, indicating that the nanoencapsulation of Pelawan stem extract has achieved nanoscale dimensions. The polydispersity index (PI) values for Pelawan stem extract formulas A, B, and C were 0.645, 0.687, and 0.476, respectively. Formula C has a PI value of less than 0.5, indicating that nanocapsules in formula C are more uniform. Formula C was the best formulation, with the smallest size and lowest PI. The Pelawan stem extract, rich in phenolic compounds, packaged in nanocapsule form through a simple nanoencapsulation process, holds potential as a future nutraceutical product.

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Nanoencapsulation of Pelawan Stem Extract (Tristaniopsis merguensis Grifft.) Using Polycaprolactone (PCL). (2025). ALKIMIA : Jurnal Ilmu Kimia Dan Terapan, 7(1). https://doi.org/10.19109/wr4fqj14
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Vol. 7 No. 1 (2023): ALKIMIA
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Nanoencapsulation of Pelawan Stem Extract (Tristaniopsis merguensis Grifft.) Using Polycaprolactone (PCL). (2025). ALKIMIA : Jurnal Ilmu Kimia Dan Terapan, 7(1). https://doi.org/10.19109/wr4fqj14

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