Nanoencapsulation of Pelawan Stem Extract (Tristaniopsis merguensis Grifft.) Using Polycaprolactone (PCL).

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Published: Feb 28, 2023
DOI: https://doi.org/10.19109/23atv291

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Robby Gus Mahardika
Universitas Bangka Belitung
Shania Shakila
Universitas Bangka Belitung
Widodo Budi Kurniawan
Universitas Bangka Belitung
Ririn Amelia
Universitas Bangka Belitung

Abstract

Formulation of nanoencapsulation using variations in the mass of Pelawan stem extract at (A) 0.15; (B) 0.25; and (C) 0.35 g combined with the addition of 0.5% PCL (Polycaprolactone) and Tween 80. Based on the analysis, the resulting nanocapsule sizes were 559.2, 447.2, and 297.0 nm, respectively, indicating that the nanoencapsulation of Pelawan stem extract has achieved nanoscale dimensions. The polydispersity index (PI) values for Pelawan stem extract formulas A, B, and C were 0.645, 0.687, and 0.476, respectively. Formula C has a PI value of less than 0.5, indicating that nanocapsules in formula C are more uniform. Formula C was the best formulation, with the smallest size and lowest PI. The Pelawan stem extract, rich in phenolic compounds, packaged in nanocapsule form through a simple nanoencapsulation process, holds potential as a future nutraceutical product.

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Nanoencapsulation of Pelawan Stem Extract (Tristaniopsis merguensis Grifft.) Using Polycaprolactone (PCL). (2023). ALKIMIA : Jurnal Ilmu Kimia Dan Terapan, 7(1), 311-316. https://doi.org/10.19109/23atv291
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Vol. 7 No. 1 (2023): ALKIMIA
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Articles
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Nanoencapsulation of Pelawan Stem Extract (Tristaniopsis merguensis Grifft.) Using Polycaprolactone (PCL). (2023). ALKIMIA : Jurnal Ilmu Kimia Dan Terapan, 7(1), 311-316. https://doi.org/10.19109/23atv291