PENGARUH NATRIUM SIKLAMAT TERHADAP HISTOPATOLOGI ORGAN MENCIT (Mus musculus) DAN SUMBANGSIHNYA PADA MATERI STRUKTUR DAN FUNGSI JARINGAN HEWAN DI SMA/MA
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Abstrak
Sweeteners are one of the components which are often added to foodstuffs. Synthetic sweeteners
are widely used in the society is sodium cyclamate. The purpose of this study was to determine the
sodium cyclamate on the histological structure of the glomerulus of mice (Mus musculus). This
research used 12 male mice (Mus musculus) with Completely Randomized Design (CRD) so there
are 4 groups (control, PI: 0,55 mg/grbb, p2: 1,1 mg/grbb, and p3: 1,65 mg/grbb) with 3 replications
for 24 days. Parameters observed were edema and comparison of area glomerulus with Bowman
capsule. The result showed that sodium cyclamate had effect to edema and tended to area
glomerulus with Bowman capsule comparization. Based on the research could be concluded that
sodium cyclamate had effect to renal histopathology. This research will be used as media in
learning process.
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